Production and Decay of the Lambda_c Charmed Baryon from Fermilab E791

Results are presented for the 500 GeV/c pion production asymmetry and polarization of the Lambda_c (anti-Lanbda_c) charmed baryon from Fermilab experiment E791. An analysis of the decay to the p anti-K pi final state is described. Resonant sub-channel fractions and phases are given and possible resonant effects in the low mass p anti-K system discussed. Significant decay to Lambda_c --> Delta++ K- establishes for the first time the importance of a W exchange mechanism in charmed baryon decay.Comment: 9th International Conference on Hadron Spectroscopy (Hadron 2001), Protvino, Russia, 25 Aug - 1 Sep 2001, LaTeX, 19 file

Estimating the minimally important difference (MID) of the Diabetes Health Profile-18 (DHP-18) for Type 1 and Type 2 Diabetes Mellitus

Aims: The DHP-18 is a widely used measure of health related quality of life in diabetes mellitus but it is unclear what constitutes a meaningful change in score on each domain. The aim of this study was to establish estimates for the minimally important difference (MID) for each of the domains. Methods: The MID for each domain was estimated using both anchor and distribution based approaches which were applied to data from both the United Kingdom and France. A range of anchors were tested. Results: A global health change anchor was found to be more acceptable for Type 1 diabetes than for Type 2. MID estimates varied by domain, by estimation approach used, and by diabetes type. For Type 1 diabetes the Psychological Distress domain estimates ranged from 2.86 to 11.05, Barriers to Activity domain from 2.87 to 11.32 and Disinhibited Eating domain from 1.03 to 11.53. For Type 2 diabetes the Psychological Distress estimates ranged from 0.94 to 9.71; Barriers to Activity from 1.66 to 9.88 and Disinhibited Eating from 0.90 to 11.64. Conclusions: This is the first attempt to derive estimates for the MID of an English language measure of health related quality of life in diabetes. For Type 1 diabetes we recommend using the mean MID value using both approaches. For Type 2 we recommend applying more weight to the distribution based estimations. The MID values identified in this study will help clinicians and researchers using the DHP-18 to identify clinically meaningful change in patient reported outcomes

A comparative analysis of two models of reading: Goodman and Guthrie

Two models of reading are compared: a psycho-linguistic model presented by Goodman (1967), and a psychological model, presented by Guthrie (1973). A review of the literature provides examples of support for, and dissent from, each model. The possibility of integrating these models is discussed. Experiment One is a partial application of a study by Allington and McGill-Franzen (1980), in which subjects are required to read aloud lists followed by equivalent texts. The results support the findings of the original study. Experiment Two is similar to Experiment One, but investigates the effects of incongruous homophones on the reading behaviour of good and weak readers. The results indicate that there is no significant difference in the extent to which incongruous homophones affect the oral reading of both good and weak readers. Both groups appear similar in their awareness of the internnal structure of words when reading texts aloud. It is concluded that reading is too complex a process to be explained solely by the models of either Goodman or Guthrie

Latrunculin A delays anaphase onset in fission yeast by disrupting an ase1-independent pathway controlling mitotic spindle stability

It has been proposed previously that latrunculin A, an inhibitor of actin polymerization, delays the onset of anaphase by causing spindle misorientation in fission yeast. However, we show that {Delta}mto1 cells, which are defective in nucleation of cytoplasmic microtubules, have profoundly misoriented spindles but are not delayed in the timing of sister chromatid separation, providing compelling evidence that fission yeast does not possess a spindle orientation checkpoint. Instead, we show that latrunculin A delays anaphase onset by disrupting interpolar microtubule stability. This effect is abolished in a latrunculin A-insensitive actin mutant and exacerbated in cells lacking Ase1, which cross-links antiparallel interpolar microtubules at the spindle midzone both before and after anaphase. These data indicate that both Ase1 and an intact actin cytoskeleton are required for preanaphase spindle stability. Finally, we show that loss of Ase1 activates a checkpoint that requires only the Mad3, Bub1, and Mph1, but not Mad1, Mad2, or Bub3 checkpoint proteins

First-Year Student Leadership Readiness Among CCCU Member Institutions Citing Leadership in Their Mission Statement

The Council of Christian Colleges and Universities has 121 members, 45 of which cite leadership as an institutional value within their mission statement; programs and curriculum are designed to help graduates attain this value as they earn a degree. Traditional-age, first-year students who enroll in these institutions may or may not hold the same view of leadership, based on past experience or training. As a new generation of students rises to enroll in these institutions, a consideration of the view of leadership held by both the institution, who have a specifically Christian worldview, and the students who enroll in them is appropriate. By comparing the view of leadership held by both institution and student, a clearer view of programming needs can be developed, in order to produce the graduate outcomes proposed by mission statements

Unmarried Fathers’ Earnings Trajectories: Does Partnership Status Matter?

Married men earn more than unmarried men. Previous research suggests that marriage itself causes some of the difference, but includes few men who fathered children out of wedlock. This paper asks whether increasing marriage (and possibly cohabitation) following a non-marital birth is likely to increase fathers’ earnings and labor supply. The analyses are based on a new birth cohort study the Fragile Families and Child Wellbeing Study which follows unmarried parents for the first five years after their child’s birth. Results provide some support for the idea that increasing marriage will lead to increased fathers’ earnings.Cohabitation, marriage, income, men, males, earnings, income, children